Issued by: South African Institute for Drug-Free Sport (SAIDS)
Date: 12th December 2014
5-methylhexan-2-amine, also known as 1,4-dimethylpentylamine, is a substance that is Prohibited
In-Competition under the World Anti-Doping Code (WADC) Prohibited List 20241. This
compound is classified under S6.B Specified Stimulants, which means that its presence in an
athlete’s urine sample would result in an anti-doping rule violation.
Background and Incident Report
The South African Institute for Drug-Free Sport (SAIDS) analysed batch 230524 of a supplement
product named CPH4 Pre-Workout sold by a South African company named V-Pharma at a
WADA-accredited laboratory who confirmed the presence of 5-methylhexan-2-amine (1,4-
dimethylpentylamine) in the dietary supplement. This ingredient is not listed on the label of the
supplement, which is misleading to Athletes.
Advisory to Athletes
Given the detection of methylhexan-2-amine (1,4-dimethylpentylamine) in this supplement,
Athletes are strongly advised to exercise caution when considering the use of dietary supplements,
especially those that do not clearly list all ingredients. Methylhexan-2-amine (1,4-
dimethylpentylamine) is a prohibited substance as per the WADC Prohibited List 2024 and is
banned in-competition. Its presence in an Athlete’s sample, regardless of intent, will result in an
anti-doping rule violation. The Strict Liability rule holds Athletes accountable for any prohibited
substance found in their bodily specimens, regardless of how or why the substance entered their
system.
The ongoing issue of mislabelling and contamination of dietary supplements presents significant
risks to Athletes. Supplement manufacturing is not regulated in South Africa, therefore, SAIDS
cannot guarantee nor advise athletes which supplement products are safe and free from
contamination.
Advice for Athletes
Athletes are encouraged to consult with a nutritionist or anti-doping expert before using any
supplement, especially when in doubt regarding its contents and to:
- Stay informed about potential recalls or warnings from SAIDS or other relevant authorities about
contaminated or mis-labelled products. - Ensure you are familiar with the current WADC Prohibited List and understand the implications
of consuming substances that may be banned in-competition. - Remain vigilant and aware of the risks involved in using dietary supplements, and to exercise
caution when considering products that do not provide full ingredient transparency.
If you are unsure of any medication and/or supplement and need assistance, please contact SAIDS
at info@saids.org.za